AOD 9604 is a modified form of Growth Hormone, which is a 191 amino acid peptide. The last 15 amino acids (176-191) of the Growth Hormone polypeptide have been reproduced as a specific peptide and is called GH Frag 176-191 or AOD 9604.
This peptide is used for burning fat and medically assisted weight loss, and it has other benefits as well.
Gland Stimulated: Pituitary Gland
Benefits of AOD 9604
While it's best known as a fat-burning peptide, there are plenty of other benefits to using AOD-9604. Here are some to note:
- Reduces body fat
- Triggers fat release from obese fat cells predominantly more than lean ones
- Mimics the way natural growth hormone regulates fat metabolism
- No adverse effects on blood sugar or growth
- Stimulates lipolysis
- Inhibits lipogenesis (the transformation of non-fatty foods into body fat)
- Favorable cartilage repair and regenerative properties, especially when paired with peptide BPC 157
How It Works
AOD-9604, also known as Tyr-hGH Frag 176-191, has been proven to have a strong fat-burning capacity without creating a desire to overeat. It doesn't affect blood sugar or tissue growth. (Heffernan 2001 Heffernan 2001, Ng 2000).
AOD-9604 activates degradation and fat burning (oxidation) by a method that doesn't use the hGH receptor; it has its own mechanism of action independent of hGH. Laboratory studies on rodents, pigs, dogs & humans have identified the AOD-9604 mechanism which triggers fat release from the obese fat cells predominantly and works to reduce the accumulation of new fat in fat cells as well as increase fat burning. What is extraordinary about the AOD-9604 is its ability to reduce abdominal fat stores.
The second most potent fat loss peptide is CJC-1295 since it leads to an increase in overall GH levels in the body (the opposite of what happens typically as individuals age).
This explains one of the reasons people have tended to gain fat as they get older. If your only goal is fat loss, it's usually best to avoid using products GHRP (GHRP-6, GHRP-2 or GHRH’s) because they may give you the side effects of increased hunger and raised cortisol. AOD-9604 does not increase hunger or raise cortisol.
AOD 9604 Research
AOD-9604 (Advanced Obesity Drug) was originally developed by Professor Frank Ng at Monash University in Australia in the 1990s, with the intent of finding an anti-obesity drug that had the fat-burning effects of human growth hormone (HGH) without the muscle-building effect.
Other recent findings have shown, in addition to its fat loss properties, AOD 9604 processes many other regenerative properties associated with growth hormone. Currently, trials are underway to show the application of AOD 9604 in osteoarthritis, hypercholesterolemia, and bone and cartilage repair.
Results of the oral glucose tolerance test demonstrated that, in contrast with hGH, AOD 9604 has no negative effect on carbohydrate metabolism. There were no anti-AOD 9604 antibodies detected in any of the patients selected for antibody assay. In none of the studies did a withdrawal or serious adverse event occur related to intake of AOD 9604.
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AOD 9604 is one of the best peptides for weight loss. It also has additional benefits that can help with fat reduction, better metabolism, and more.
AOD 9604 displayed a very good safety and tolerability profile indistinguishable from the placebo. AOD 9604 did not result in any of the adverse effects associated with full-length hGH treatment. AOD 9604 has an excellent safety profile, recently obtaining Human GRAS status in the USA.