What is Neuroinflammation?
Neuroinflammation is inflammation of the central nervous system tissue. This leads to neuronal dysfunction, neuronal injury and eventually neuronal death. Causes of neuroinflammation include toxins, viruses, bacteria, stress, autoimmune conditions, traumatic brain injuries, and aging.
Chronic inflammation in the neuronal tissue is what leads to damage and neurodegenerative conditions. Common conditions include:
- Parkinson’s disease
- Alzheimer's disease & dementia
- Amyotrophic lateral sclerosis (ALS)
- Traumatic brain injury (TBI)
- Transient ischemic attack (TIA)
- Memory impairment
- Brain fog
- Chronic fatigue
- Autoimmune disease
- Learning difficulties
Critical Functions, Crucial Implications
The prevalence of neurodegenerative diseases are far reaching and can have devastating implications. Traumatic brain injury (TBI), for example, is a leading cause of injury, death and disability in the U.S.
Even without TBI, neurodegeneration affects many. As we age, memory impairment is a consequence of decline in neuronal function and increase in neurodegeneration. Oxidative stress is a major factor in brain aging and memory impairment. And more than one million adults in the U.S. are diagnosed annually with a chronic brain disease or disorder, with Alzheimer’s disease being the most prevalent cause of adult-onset brain disorders.
The support of healthy neurological function is crucial, which is why scientists are considering the importance of inflammation and apoptosis in neurodegenerative conditions.
Decreasing Neuroinflammation with Synapsin
Synapsin is a term often used to describe the combination of two products, Rg3 and Nicotinamide Ribose (NR). (credit: J. LaValle)
Rg3 is one of several triterpene saponins (ginsenosides) extracted from the root of ginseng. Laboratory studies show that Rg3 extracted from Panax ginseng supports nerve cells, helps support healthy microglial activity, healthy neuronal function and decreases microglia activation and neuroinflammatory processes. Rg3 is Neuroprotective and decreases oxidative stress of neurological tissue.
Nicotinamide riboside (NR) is a form of vitamin B3. NR supports healthy synthesis of NAD+ in human cells. Studies demonstrate the supportive and neuroprotective effect of NAD+. NR is Neuroprotective, it helps increase neuronal NAD+ production and decrease neuronal degeneration.
Benefits of Synapsin
There are powerful benefits that come from the use of synapsin to reduce neuroinflammation and support cognitive function. Here's an overview of some of the key ways synapsin helps patients.
- Neuroprotection / Cognitive support
- May improve Traumatic Brain Injury (TBI) neuroinflammation recovery
- Can aid in memory improvement
- Helps improve brain fog
- Stroke / TIA recovery
- Support for cognitive decline and related conditions (Dementia, Alzheimer’s Disease, ALS)
- Helps improve NAD+ production in the central and peripheral nervous system and regulate sirtuin expression
- Improves mitochondrial function
- Decreases microglial activation and subsequent oxidative stress and neuronal inflammation
- Improves methylation and decreases homocysteine formation. Elevated homocysteine levels are reported to increase cognitive decline including those with Alzheimer’s Disease and vascular dementia
Synapsin comes as a nasal spray and is administered daily. It is commonly mixed with vitamin B12 (methylcobalamin) to aid in healthy homocysteine levels and improved methylation processes.
Synapsin can be a powerful option If you struggle with memory issues, concentration or focus; or have concerns about dementia or age-related neurologic disorders. It works to stimulate brain healing and repair. RG3 + NAD is one of the best options to stimulate neuroregeneration.
Contact Transformyou to learn more about our options to support your health.
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