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Bontril (Phendimetrazine) is an FDA-approved appetite suppressant.  It is an sympathomimetic amine, similar to an amphetamine.


Bontril works to stimulate the central nervous system to increase your heart rate and blood pressure. Those, in turn, decrease your appetite. Bontril is a treatment for obesity and should only be used as a short-term supplement to diet and exercise.

Appetite Suppressants such as Bontril, in addition to others like Diethylpropion, BenzphetaminePhentermine and Qsymia, should NOT be used as a substitute for proper diet or exercise. For maximum effects, they must be used in conjunction with a reduced-calorie diet and/or exercise.

You should not use Bontril if you have heart problems or heart disease, high blood pressure, hyperthyroidism, a history of drug abuse, or glaucoma. Bontril can interact with several medications, so be sure to tell your doctor about all drugs you take. 

Bontril should only be used under doctor supervision. 

Common Side Effects

Like all prescription appetite suppressants, there are common side effects. Bontril side effects can include:

  • trouble sleeping
  • dizziness 
  • tremors
  • hyperactivity or restlessness
  • upset stomach, nausea, or constipation
  • dry mouth
  • blurred vision
  • headache

Your doctor can tell you about other potential side effects. Additionally, you should be aware of certain side effects that your doctor will want you to contact about, including changes in mood, heart fluttering or pounding, changes in urination, or increased blood pressure. 

Any modifications in your diet, activity level, and behavior must be developed and continued long-term in order to continue losing weight and prevent the lost weight from returning. Transformyou will help you stay on-track with your medical weight loss goals, checking in on you frequently regarding your general health, weight, etc. and adjusting your medical weight loss plan according to your needs. 

All patients always work directly with one of our licensed physicians to ensure patient safety and confidentiality.

The Controlled Substances Prescription Monitoring Program (CSPMP) is a program developed to promote the public health and welfare by detecting diversion, abuse and misuse of prescription medications classified as controlled substances under the Arizona Uniform Controlled Substances Act.  Every Physician who possesses a DEA registration is required to also possess a CSPMP registration issued by the Arizona Board of Pharmacy. At transformyou, we adhere to Arizona's CSPMP policy before prescribing a controlled substance to any patient.